Correction: Efficacy of N-Acetyl Cysteine in Traumatic Brain Injury
نویسندگان
چکیده
Citation: The PLOS ONE Staff (2014) Correction: Efficacy of N-Acetyl Cysteine in Traumatic Brain Injury. PLoS ONE 9(7): e104353. doi:10.1371/journal.pone.0104353 Published July 28, 2014 Copyright: 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
منابع مشابه
The Efficacy of N-Acetyl-Cysteine (NAC) Supplementation in FST Model for Screening Antidepressants
Introduction: The model for screening antidepressant-like activity in pre-clinical drug studies include, rat forced swimming test (FST). The reports on N-acetylcysteine (NAC) as an antioxidant supplement in stress related disorder is well documented. This study was aimed at potential antidepressant mechanism of N- Acetyl Cysteine (NAC), a glutamate precursor on FST animal model for screening an...
متن کاملEfficacy of N-Acetyl Cysteine in Traumatic Brain Injury
In this study, using two different injury models in two different species, we found that early post-injury treatment with N-Acetyl Cysteine (NAC) reversed the behavioral deficits associated with the TBI. These data suggest generalization of a protocol similar to our recent clinical trial with NAC in blast-induced mTBI in a battlefield setting, to mild concussion from blunt trauma. This study us...
متن کاملProtective Effect of N-Acetyl Cysteine in Carbon Tetrachloride-Induced Hepatotoxicity in Rats
The present study determines the efficacy of N-acetyl cysteine (NAC) on marker enzymes, lipid peroxidation and antioxidants in carbon tetrachloride induced hepatotoxicity in rats. Carbon tetrachloride (CCl4) (3 mL/kg/week) administered subcutaneously to albino Wistar rats for a period of three months significantly increased the activities of marker enzymes in plasma such as aspartate transamina...
متن کاملP33: The Effect of Boswellia Serrata Extract and AKBA (Acetyl-11-keto-β-Boswellic Acid) on the Neurological Scores, Brain Edema and Brain -Blood Barrier after Severe Traumatic Brain Injury in Male Rats: the Role of IL-1β and IL-10
Boswellia serrataBoswellia serrata has a prominent role in TBI outcome’s and perhaps protect neurons through modulating inflammatory and antioxidant pathways
متن کاملAmelioration of Acute Sequelae of Blast Induced Mild Traumatic Brain Injury by N-Acetyl Cysteine: A Double-Blind, Placebo Controlled Study
BACKGROUND Mild traumatic brain injury (mTBI) secondary to blast exposure is the most common battlefield injury in Southwest Asia. There has been little prospective work in the combat setting to test the efficacy of new countermeasures. The goal of this study was to compare the efficacy of N-acetyl cysteine (NAC) versus placebo on the symptoms associated with blast exposure mTBI in a combat set...
متن کامل